Abstrak:
A debilitating complication of diabetes mellitus is diabetic ulcers, which leads to increased overall morbidity in patients. Patients with diabetes mellitus (type 1 or 2) have a total lifetime risk of a diabetic foot ulcer complication as high as 25%. Method this case study used experimental design, the patient is Mr F. with DFU. The spray nozzle was pointed about 10 centimetres from the wound and a thin layer of SiO2 - + Ag+ + Chlorhexidine + Hyaluronic acid was dispersed, covering the entire wound surface. Precaution was taken not to massage or rub the mixture into the wounds. The wounds were then covered with non-adhesive dressing. Result there was rapid wound healing evidenced by absence of infection, presence of granulation, reduction of wound size as well as reduction in pain within a periode of time 1 month. Conclusion the patented formulation of SiO2 - + Ag+ + chlorhexidine + hyaluronic acid was proven to be effective due to significant wound size reduction, absence of infection and presence of granulation as shown in current case series. The Kadermin spray exhibit broad spectrum antimicrobial properties of silver coupled with antiseptic properties of chlorhexidine, moisturising properties of hyaluronic acid as well as protective barrier of silicon dioxide.
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