Abstrak:
Collagen, a key component of the extracellular matrix, plays critical roles in the regulation of the phases of wound healing has been utilized as an adjunct wound therapy to promote healing. Aloe vera gel can not only increase the amount of collagen in wounds but also change the composition of collagen, increase collagen cross-linking and thereby promote wound healing. Scientific studies have shown that the gel can increase the flexibility and reduce the fragility of the skin since 99% of the gel is water. Meanwhile red fruit oil (RFO) can be used to speed up wound healing because it contains tocopherols, carotenoids, oleic acid, linoleic acid and linolenic acid. Alveda collagen gel is a biotechnology innovation product that combines type I fish collagen, aloe vera barbadensis and Red Fruit Oil in a gel preparation that is used to treat wounds, both acute and chronic wounds. Objective in this work we summarize four case studies of the use of Alveda collagen gel products for the treatment of diabetic ulcers and other chronic wounds at Griya PUSPA Wound Care Yogyakarta. Methode case study. Results of the 4 cases of chronic wounds treated with ALVEDA Collagen Gel, satisfactory results were obtained, 2 wounds healed and 2 wounds reached the re-epithelialization phase. Conclussion ALVEDA Collagen Gel is effective as a primary dressing for wounds in the proliferation and re-epithelialization phases
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